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Thị Thu Trang, p ., Thanh Đức, L. ., và Thị Thanh Bình, H. . (2022). KẾT QUẢ ĐIỀU TRỊ UNG THƯ NỘI MẠC TỬ CUNG GIAI ĐOẠN III TẠI BỆNH VIỆN K. Tập san Y học Việt Nam, 513(2). Https://doi.org/10.51298/vmj.v513i2.2478

Mục tiêu: Nhận xét một số đặc điểm lâm sàng, cận lâm sàng của bệnh nhân (BN) ung thư nội mạc tử cung (UTNMTC) tiến độ III tại cơ sở y tế K. Đánh giá tác dụng điều trị nhóm người mắc bệnh nghiên cứu. Bệnh nhân và đối tượng nghiên cứu: 60 người bệnh UTNMTC tiến trình III điều trị tại khám đa khoa K từ thời điểm tháng 1 năm 2016 đến mon 12 năm 2020, được chữa bệnh đủ thời gian chữa trị phẫu thuật, xạ trị té trợ, hóa trị ngã trợ, được theo dõi và quan sát sau điều trị. Kết quả: Tuổi vừa phải 56 tuổi, triệu bệnh lâm sàng hay chạm mặt nhất là ra máu cửa mình bất thường.60% BN có nồng độ CA12.5 ngày tiết trước điều trị ở tầm mức cao (trên 35 U/ml). Ung thư biểu mô (UTBM) con đường dạng nội mạc là thể mô bệnh dịch học (MBH) hay chạm chán nhất, 73,34%. BN có ER dương tính chỉ chiếm 59,52%, truyền bá dương tính 54,76%. Trung vị thời gian sống không dịch là 30,86±4,20, với 95%CI (22,63-39,10). BN ở tiến độ IIIA/B có tiên lượng tốt hơn BN ở tiến độ IIIC. BN gồm TTNT dương tính tiên lượng xuất sắc hơn. Nồng độ CA12.5 tăng vọt là nguyên tố tiên lượng xấu vào UTNMTC. Kết luận: UTNMTC quy trình III sau khoản thời gian được chữa bệnh đúng với đủ liệu trình sẽ kéo dãn dài thời gian sống thêm không bệnh.


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Từ khóa

Ung thư nội mạc tử cung giai đoạn III, sống thêm không căn bệnh


Tài liệu tham khảo


1.https://seer.cancer.gov/statfacts/html/corp.html.2.Trần Văn Thuấn. Ung Thư học tập Đại Cương.3.Vũ Đình Giáp. Dìm xét kết quả điều trị ung thư nội mạc tử cung tiến độ III, IV tại cơ sở y tế K. Luận văn thạc sỹ y học chăm ngành ung thư, trường Đại học tập Y hà Nội. Published online 2016.4.H. Hricak, L. V. Rubinstein, G. M. Gherman, et al (1991). MR imaging evaluation of endometrial carcinoma: results of an NCI cooperative study. Radiology, 179 (3), 829-832.5.J M Duk etal, “ CA 125: a useful marker in endometrial carcinoma”. Am J Obstet Gynecol năm nhâm thìn Nov15551097-102 Doi 1010160002-93788690358-3.6.Lê Văn Phúc (2011). Nghiên cứu đặc điểm mô bệnh học và tỷ lệ biểu thị các thụ thể ER, lăng xê trong ung thư biểu mô nội mạc tử cung, Luận văn thạc sỹ Y học, siêng ngành phẫu thuật bệnh, ngôi trường Đại học Y Hà Nội7.Caifeng Wang et al, “ Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Markers in Endometrial Cancer”, J Cancer. 2020 Jan 16;11(7):1693-17018.Ulas Solmaz. Lymphovascular space invasion & positive pelvic lymph nodes are independent risk factors for para-aortic nodal metastasis in endometrioid endometrial cancer. Eur J Obstet Gynecol Reprod Biol năm ngoái Mar18663-7 Doi 101016jejogrb201501006 Epub năm ngoái Jan 23.9.Outcomes of patients with surgically and pathologically staged IIIA-IVB pure endometrioid-type endometrial cancer: a Taiwanese Gynecology Oncology Group (TGOG-2005) Retrospective Cohort Study (A STROBE-Compliant Article). April 2016Medicine 9515e3330 DOI101097MD 0000000000003330. Published online 2016.

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Ung thư nội mạc tử cung là loại ung thư phụ khoa thường chạm mặt nhất. Ngày nay, với nguy cơ tiềm ẩn thừa cân nặng và mập mạp ngày càng tăng, người thanh nữ càng tăng tài năng mắc buộc phải ung thư nội mạc tử cung. Xuất huyết âm đạo phi lý là triệu hội chứng sớm và thường gặp của bệnh tật này. Bạn bệnh có thời cơ điều trị triệt nhằm và bớt thiểu nguy cơ tiềm ẩn tái phát giả dụ được vạc hiện bệnh dịch ở giai đoạn sớm.

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